Dr. Jill Sible

Professional
Personal

---

Professional top

Curriculum Vitae

Jill C. Sible
Department of Biological Sciences, Derring Hall
Virginia Polytechnic Institute and State University
Blacksburg, VA 24061-0406
Phone: (540) 231-1842, FAX: (540) 231-9307, E-mail: siblej@vt.edu

Education

Tufts University School of Medicine, 1995
Ph.D. in Cell, Molecular and Developmental Biology, Advisor: Dr. Noelynn Oliver
Thesis: Fibronectin gene expression during normal and abnormal wound healing.

University of New Hampshire, 1990
B.S. in Biochemistry, Summa Cum Laude, Advisor: Dr. Charles Walker
Research: Regulation of ornithine decarboxylase during sea star spermatogenesis.

Professional Experience

Assistant Professor of Biology, Virginia Tech, 1998-present
Research: Cell cycle regulation during the early development of Xenopus laevis.

Postdoctoral Fellow, Howard Hughes Medical Institute, 1995-1998
University of Colorado Health Sciences Center, Advisor: Dr. James Maller
Research: Cell cycle and cell death pathways at the midblastula transition in Xenopus laevis.

Current Funding (major external sources)

National Institute of Health GM59688 - Cell cycle checkpoints in the Xenopusembryo
PI: Sible; Dates of funding: 5/1/00-4/30/04
Total award: $560,322

DARPA/ITO - The eukaryotic cell cycle as a test case for modeling cellular regulation in a collaborative problem-solving environment
PI: Tyson, Co-PIs - Sible and others; Dates of funding: 9/1/01 - 12/30/03
Total award: $1,650,000; Sible’s portion: $144,000

PA-98-024: Supplements for the Study of Complex Biological Systems
NIH - Cell cycle checkpoints in the Xenopus embryo: molecular mechanisms and mathematical models
PI: Sible, Co-PI: Tyson; Dates of funding: 5/1/02-4/30/04
Total award: $211,140

PA-01-079: NIH: Research Supplements for Underrepresented Minorities
PI: Sible, Student applicant: Carter; Dates of funding 6/1/02-4/30/04
Total award: $75,915

Honors and Awards

1989-1990 Undergraduate Research Opportunities Program (UROP) Fellowship
  Summer Undergraduate Research Fellowship (SURF)
1991-1995 Howard Hughes Predoctoral Fellow
1994 Keynote Speaker, Third Annual College of Life Science and Agriculture Undergraduate Research Conference, University of New Hampshire
1995-1998 Howard Hughes Postdoctoral Fellow
1999  Ralph E. Powe Junior Faculty Enhancement Award
  Oak Ridge Associated Universities
2001 Biology Department Outstanding Teacher Award
2002 Biology Department Most Effective Teacher Award

Courses Taught

BIOL 2104 Cell and Molecular Biology
BIOL 6024 Molecular Biology of the Cell Cycle (and Cancer)
BIOL 6024 Current Issues in Cell Biology

Committee Assignments

1998-2000 Department Seminar Committee
1999-2001 Graduate Selection Committee
1999-present Department Animal Care Committee
2000-present Department Alumni Advisory Committee
2001-2002 Department Executive Committee
2001-2002 Computer Science, Bioinformatics Search Committee
2001-2002 University Biomedical Committee, Chair Cell Cycle Subcommittee
2002-present University Biomedical and Public Health Implementation Committee
2002-present Department Diversity Committee
2002-present Coordinating Council for the Mid Eastern Alliance for Minority Participation (MEAMP)

Publications

Sible JC, AG Marsh, and CW Walker (1991) Effect of extrinsic polyamines on post-spawning testes of the sea star, Asterias vulgaris  (Echinodermata): implications for the seasonal regulation of spermatogenesis. Invertebrate Reproduction and Development 19: 257-264.

Sible JC, E Eriksson, SP Smith, and N Oliver (1994) Fibronectin gene expression differs in normal and abnormal wound healing. Wound Repair and Regeneration 2: 3-19.

Sible JC, WJ Rettig, E Eriksson, SP Smith, and N Oliver (1995) Gene expression of tenascin is altered in normal scars and keloids. Wound Repair and Regeneration 3: 37-48.

Sible JC, E Eriksson, and N Oliver (1996) DNA-binding proteins from keloid fibroblasts form unique complexes with the human fibronectin promoter. Gene Expression 5: 269-283.

Hartley RS, JC Sible, AL Lewellyn, and JL Maller (1997) A role for cyclin E/Cdk2 as a developmental timer in Xenopus embryos. Developmental Biology 188: 312-321.

Sible JC, JA Anderson, AL Lewellyn, and JL Maller (1997) Zygotic transcription is required to block a maternal program of apoptosis in Xenopus embryos. Developmental Biology 189: 335-346.

Sible JC, E Erikson, M Hendrickson, JL Maller, and J Gautier (1998) Developmental regulation of MCM replication factors in Xenopus laevis. Current Biology 8:347-350.

Kappas N, P Savage, KC Chen, AT Walls, and JC Sible (2000) Dissection of the XChk1 signaling pathway in Xenopus laevis embryos. Molecular Biology of the Cell 11: 3101-3108.

B Novák, JC Sible, and JJ Tyson (2002 ) Checkpoints in the Cell Cycle. In: Encyclopedia of Life Sciences. London: Nature Publishing Group. http://www.els.net/

Sha W, J Moore, K Chen, AD Lassaletta, C-S Yi, JJ Tyson, and JC Sible (2003) Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts. Proceedings of the National Academy of Science 100: 975-980 (on line early release December 30, 2002 http://www.pnas.org).

PNAS commentary on Sha et al. by Mark Solomon

AD Carter and JC Sible (2003) Loss of XChk1 function leads to apoptosis after the midblastula transition in Xenopus embryos.  Mechanisms of Development 120: 315-323.

A Ciliberto, MA Petrus, JJ Tyson and JC Sible (2002) A kinetic model of the cyclin E/Cdk2 developmental timer in Xenopus laevis embryos.  Biophysical Chemistry 104: 573-589.

Storrie B, B Wong, RA Walker, G Gillaspy, JC Sible, and M Lederman (2003) Working with Molecular Cell Biology: A Student Companion and Solutions Manual.  New York: W. H. Freeman.

Storrie B, B Wong, RA Walker, G Gillaspy, JC Sible, and M Lederman (2003) Testing on Molecular Cell Biology.  New York: W. H. Freeman.

Contributor, End-of-Chapter questions for five chapters of H. Lodish et al.  (2003) Molecular Cell Biology, 5th ed. New York: W. H. Freeman.

Allen N, L Calzone, KC Chen, A Ciliberto, N Ramakrishnan, CA Shaffer, JC Sible, JJ Tyson, M Vass, LT Watson, and J Zwolak (2003) Modeling regulatory networks at Virginia Tech. submitted to: Omics.

Petrus MA, DE Wilhelm, M Murakami, NC Kappas, AD Carter, BN Wroble, and JC Sible (2003) Altered expression of Chk1 disrupts cell cycle remodeling at the midblastula transition in Xenopus laevis embryos.  submitted to: Cell Cycle.

Personal top

my little tadpoles :)