Recent Publications

J Zwolak, N Adjerid†, EZ. Bagci, JJ. Tyson, and JC. Sible* (2009) A quantitative model of the effect of unreplicated DNA on cell cycle progression in frog egg extracts, Journal of Theoretical Biology, in press.

JC Sible* and BN Wroble† (2009) Chapter 1: Expression of exogenous mRNA in Xenopus laevis embryos for the study of cell cycle regulation. Methods in Molecular Biology: Microinjection Techniques, Vol. 518; 1 – 15. Humana Press: Totowa, NJ.

Chen Y†, FM McNabb, and JC Sible (2009) Percholorate exposure induces hypothyroidism and affects thyroid-responsive genes in liver but not brain of quail chicks. Archives of Environmental Contamination and Toxicology, DOI: 10.1007/s00244-009-9304-0, epub ahead of print. (link to article)

Chen Y†, JC Sible, and FM McNabb (2008) Effects of maternal exposure to ammonium perchlorate on thyroid function and the expression of thyroid-responsive genes in Japanese quail embryos. General and Comparative Endocrinology, 159:196-207. (link to article)

Tyson, JJ, R Albert, A Goldbeter, P Ruoff, and J Sible (2008) Biological switches and clocks: preface to the special issue. Interface: Journal of the Royal Society, 5 Suppl 1: S1 – S8. (link to article)

Adjerid N†, BN Wroble†, and JC Sible* (2008) Chk1 is activated at the midblastula transition in Xenopus laevis embryos independent of DNA content and the cyclin E developmental timer. Cell Cycle, 7: 1112-1116. (link to article)

Wroble BN†, CV Finkielstein and JC Sible* (2007) Wee1 kinase alters cyclin E/Cdk2 and promotes apoptosis during the early embryonic development of Xenopus laevis. BMC Developmental Biology 7:119, doi:10.1186/1471-213X-7-119 (link to article)

Sible JC* and JJ Tyson (2007) Mathematical modeling as a tool for investigating cell cycle control networks. Methods 41:238-247. (link to article)

Lederman M, JC Sible, DE Wilhelm† and L Spotswood (2007) Biological diversity in Brunson, D., L.L. Lampl, and B. Jarmon eds. Letters from the Future: Linking Students and Teaching with the Diversity of Everyday Life. Stylus: Sterling VA, pp. 45-70.

Carter, AD†, BN Wroble†, and JC Sible* (2006) Cyclin A1/Cdk2 is sufficient but not required to induce apoptosis in Xenopus laevis embryos, Cell Cycle, 5:2230-2236. (link to article)

Sible JC*, DE Wilhelm†, and M Lederman (2006) Teaching cell and molecular biology for gender equity. Cell Biology Education 5:227-238. (link to article)

Wroble BN and JC Sible* (2005) Chk2/Cds1 protein kinase blocks apoptosis during early development of Xenopus laevis, Developmental Dynamics 233:1359-1365. (link to article)

Petrus† MA, DE Wilhelm†, M Murakami, NC Kappas†, AD Carter†, BN Wroble†, and JC Sible* (2004) Altered expression of Chk1 disrupts cell cycle remodeling at the midblastula transition in Xenopus laevis embryos. Cell Cycle 3: 212-217. (link to article)

Sha† W, J Moore, K Chen, AD Lassaletta†, C-S Yi, JJ Tyson, and JC Sible* (2003) Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts. Proceedings of the National Academy of Science 100: 975-980. (link to article)

Carter† AD and JC Sible* (2003) Loss of XChk1 function leads to apoptosis after the midblastula transition in Xenopus embryos.  Mechanisms of Development 120: 315-323. (link to article)

Sible, JC* (2003) News and Views: Thanks for the memory. Nature, 426:392-393. (link to article)

Ciliberto A, MA Petrus†, JJ Tyson and JC Sible* (2003) A kinetic model of the cyclin E/Cdk2 developmental timer in Xenopus laevis embryos. Biophysical Chemistry 104: 573-589. (link to article)

Allen N, L Calzone, KC Chen, A Ciliberto, N Ramakrishnan, CA Shaffer, JC Sible, JJ Tyson, M Vass, LT Watson, and J Zwolak (2003) Modeling regulatory networks at Virginia Tech. OMICS: A Journal of Integrative Biology 7: 285-299.

Novák B, JC Sible, and JJ Tyson (2002) Checkpoints in the Cell Cycle. In: Encyclopedia of Life Sciences. London: Nature Publishing Group. http://www.els.net/ (link to article)

Kappas† N, P Savage†, KC Chen, AT Walls†, and JC Sible* (2000) Dissection of the XChk1 signaling pathway in Xenopus laevis embryos. Molecular Biology of the Cell 11: 3101-3108. (link to article)

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