Lectures

Stochastic Models of Cell Cycle Regulation in Eukaryotes

given on Nov 5, 2008, at VBI, Virginia Tech, Blacksburg, VA.

Why do we need stochastic models for cell cycle regulation?
Stochastic models of cell cycle control in budding yeast.

Practical Bifurcation Theory

8 lectures given weekly at Virginia Tech, Blacksburg, VA. (Oct. 6-Dec. 1, 2008)

1: Local Bifurcations--saddle node bifurcations.
2: Hopf bifurcations.
3A: Floquet multipliers--period doubling, torus and cyclic fold bifurcations.
3B: Global bifurcations--homoclinic and heteroclinic orbits.
4A: Codimension Two bifurcations--Cusp, Takens Bogdanov, Degenerate Hopf
4B: How do 1-p bifurcation diagrams fit together at DH and TB points.
5: An example by Guckenheimer on multiple bifurcations for chemical reactors.
6A: More on Codimension Two bifurcations--TB and Saddle-Node-Loop
6B: Fold-Hopf bifurcations.
7: Fold-Hopf bifurcations continued. Case 1 and 2.
8: Fold-Hopf bifurcations, Case 3 and 4.

Network Dynamics and Cell Physiology

given at Institute for Mathematics and Its Applications (IMA), Univ. of Minnesota, St. Paul, MN, April 17-18, 2008.

Cell physiology, molecular biology and modeling.
Network motifs: sniffers, buzzers, toggles and blinkers.
Cell cycle regulation.

Biological Switches and Clocks

given at Kavli Institute for Theoretical Physics (KITP) program, UC Santa Barbara, CA, Jul 2 - Aug 10, 2007.

Biological switches
Cell cycle regulation

Control of Cell Growth, Division and Death

given at Mathematical Biosciences Institute (MBI), Ohio State Univerisity, Columbus, OH, Sep 29 - Oct 3, 2003

Modeling the cell cycle engine and checkpoints in yeast cells.
Modeling cell growth, diviions and morphology in fission yeast.

Miscellaneous Lectures


2008. New frontiers in system biology. (slides)
2008. How do cells compute? (slides)
2006. Network dynamics and cell physiology. (slides)
1999. Coping with complexity. (slides)
1998. Commencement speech at Virginia Tech on Dec. 18. (pdf or html)