Recent publications from the Winkel lab ...

Gordon Research Conference on Macromolecular Organization and Cell Function, Oxford, UK, August 2008.

Brad Howard, Pete Bowerman, Kevin Crosby, and Melissa Ramirez at their posters.

Mel, Pete, Brad, and Kevin in
front of the gate to Addison's
walk.

FLAVONOID METABOLISM

Owens DK, Alerding AB, Crosby KC, Bandara AB, Westwood JH, Winkel BSJ. 2008. Functional analysis of a predicted flavonol synthase gene family in Arabidopsis. Plant Physiol. 147:1046-1061. [pubmed]

Owens DK, Crosby KC, Runac J, Howard BA, Winkel BSJ. 2008. Biochemical and genetic characterization of Arabidopsis flavanone 3beta-hydroxylase. Plant Physiol Biochem.46:833-843. [pubmed]

Dana CD, Bevan DR, and Winkel BSJ.  2006. Molecular modeling of the effects of mutant alleles on chalcone synthase protein structure.  J. Mol.Model., 12:905-14. [pubmed]  

Winkel BSJ. 2006. The biosynthesis of flavonoids, in E. Grotewold (ed.), The Science of Flavonoids. Springer Science & Business Media New York, NY), pp. 71-95.

Saslowsky DE, Warek U, and Winkel BSJ.  2005. Nuclear localization of flavonoid enzymes in Arabidopsis. J. Biol. Chem., 280: 23735–23740. [pubmed]  

Santos MO, Crosby WL, and Winkel B. 2004. Use of a phage-derived antibody to modulate flavonoid biosynthesis in Arabidopsis, Mol. Breed., 13: 333-343. 

Winkel BSJ.  2004.  Metabolic channeling in plants. Ann. Rev. Plant Biol., 55: 85-107. [pubmed]

Winkel-Shirley B. 2002. Biosynthesis of flavonoids and effects of stress.  Curr. Opin. Plant Biol., 5:  218-223. [pubmed]

Winkel-Shirley B.  2001. Flavonoid biosynthesis: a colorful model for genetics, biochemistry, cell biology and biotechnology.  Plant Physiol., 126:  485–493. [pubmed]

Saslowsky D, and Winkel-Shirley B.  2001. Organization of flavonoid metabolism in Arabidopsis: Subcellular localization of chalcone synthase and chalcone isomerase, Plant J., 27:  37-48. [pubmed]

Winkel-Shirley B.  2001. It takes a garden: How work on diverse plant species has contributed to an understanding of flavonoid metabolism.  Plant Physiol. 127: 1399-1404.  [pubmed]

ASSEMBLY OF FE-S CLUSTERS

Frazzon AP, Ramirez MV, Warek U, Balk J, Frazzon J, Dean DR, Winkel BS. 2007. Functional analysis of Arabidopsis genes involved in mitochondrial iron-sulfur cluster assembly. Plant Mol Biol. 2007 Apr 7; Epub ahead of print. [pubmed]

MULTIMETALLIC COMPLEXES

Jain A, Slebodnick C, Winkel BSJ, Brewer KJ. 2008. Enhanced DNA photocleavage properties of Ru(II) terpyridine complexes upon incorporation of methylphenyl substituted terpyridine and/or the polyazine bridging ligand dpp (2,3-bis(2-pyridyl)pyrazine). J Inorg Biochem. 102:1854-1861. [pubmed]

Prussin AJ 2nd, Zigler DF, Jain A, Brown JR, Winkel BSJ, Brewer KJ. 2008. Photochemical methods to assay DNA photocleavage using supercoiled pUC18 DNA and LED or xenon arc lamp excitation. J Inorg Biochem. 2008 102(4):731-739. [pubmed]

Jain A, Winkel BS, Brewer KJ. 2007. In vivo inhibition of E. coli growth by a Ru(II)/Pt(II) supramolecule [(tpy)RuCl(dpp)PtCl2](PF6).J Inorg Biochem.101:1525-1528. [pubmed]

Miao R, Mongelli MT, Zigler DF, Winkel BS, Brewer KJ. 2006. A multifunctional tetrametallic Ru-Pt supramolecular complex exhibiting both DNA binding and photocleavage. Inorg Chem. 45:10413-10415. [pubmed].

Mongelli MT, Heinecke J, Mayfield S, Okyere B, Winkel BSJ, Brewer KJ. 2006.   Variation of DNA photocleavage efficiency for [(TL)2Ru(dpp)]2+ complexes where TL = 2,2’-bipyridine, 1,0-phenanthroline, or 4,7-diphenyl-1,10-phenenthroline. J Inorg Biochem. 100:1983-1987. [pubmed]

Williams RL, Toft HN, Winkel B, Brewer KJ. 2003 Synthesis, characterization, and DNA binding properties of a series of Ru, Pt mixed-metal complexes. Inorg. Chem., 42: 4394-4400. [pubmed]

Fang Z, Swavey S, Holder A, Winkel B, Brewer KJ. 2002. DNA binding of mixed-metal supramolecular Ru,Pt complexes. Inorg. Chem. Comm., 5:1078-1081.