Faculty Members and Research

falkinham_lab

Joe Falkinham
Professor of Biological Sciences

Epidemiology, physiology, genetics and ecology of nontuberculous mycobacteria; antibiotic discovery and development

Caroline N Jones, Assistant Professor, Biological Sciences.

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Caroline Jones
Assistant Professor of Biological Sciences

Immunology and Infectious Diseases, Inflammation, Lab-on-a-chip technology, Host-pathogen interactions

li_lab

Liwu Li
Professor of Biological Sciences

Molecular pathways controlling innate immunity and inflammation; dynamic programming of innate immune leukocytes; pathogenesis of actue chronic inflammatory diseases such as sepsis and atherosclerosis

Stephen Melville
Associate Professor of Biological Sciences

Molecular pathogenesis of diseases caused by the anaerobic bacterium, Clostridium perfringens. The emphasis is on C. perfringens' interactions with host phagocytic cells and the regulation of virulence factors that lead to tissue infections and food poisoning caused by the bacterium.

popham_lab

David Popham
Professor of Biological Sciences

Structure, synthesis, and hydrolysis of the peptidoglycan wall components of vegetative cells and endospores. Studies utilize the model Gram-positive bacterium Bacillus subtilis and the pathogens Bacilus anthracis and Clostridium difficile. Molecular genetic techniques are used to identify and manipulate the genes encoding the enzymes that polymerize and hydrolyze the peptidoglycan. Biochemical methods are used to examine the activities of these proteins and the peptidoglycan structural alterations associated with genetic and phenotypic changes. Potential applications for this research are in antibiotic design and in spore-killing for decontamination procedures.

scharf_lab

Birgit Scharf
Associate Professor of Biological Sciences

Bacterial motility and chemotaxis; sensing of environmental signals, two-component signal transduction, the speed-variable flagellar motor, flagellotropic phage infection, function of type IV pili in symbiosis, tumor-targeting Salmonella

schubot_lab

Florian Schubot
Associate Professor of Biological Sciences

Structural and biophysical basis for virulence mechanisms in bacterial pathogens; regulation of the type III secretion system and biofilm formation in Pseudomonas aeruginosa; structural studies of chlamydial Inc proteins and their role in host invasion

stevens_lab

Ann Stevens
Professor of Biological Sciences

Bacterial-host interactions; cell-cell communication; molecular microbiology; emphasis on bacterial environmental sensing and gene regulation, including quorum sensing; virulence of the corn pathogen Pantoea stewartii and the human foodborne pathogen Vibrio parahaemolyticus; beneficial roles of bacteria in aquaculture

yang_lab

Zhaomin Yang
Associate Professor of Biological Sciences

Bacterial locomotion and signal transduction; Myxococcus xanthus inter- and intra-cellular signaling in fruiting and gliding motility (bacterial SURFACE motility WITHOUT the flagellum). Twitching motility and pathogenesis of Pseudomonas aeruginosa.