Iulia M. Lazar

Associate Professor of Biological Sciences
2011 Integrated Life Sciences Building (MC 0913)
1981 Kraft Drive
Blacksburg, VA 24060

Major Fields of Interest

Oncoproteomics, breast cancer cell cycle, signaling, biomarker discovery, development of advanced mass spectrometry and microfluidic technologies for the interrogation of biological systems

Current Research

Cancer is a disease of the cell cycle that results in uncontrolled proliferation of cells. In our laboratory, we explore the molecular mechanisms of breast cancer cell cycle regulation by using holistic, mass spectrometry-based systems biology approaches. We develop proteomic technologies for investigating the pathways that enable cancer cells to bypass tightly regulated molecular checkpoints, proliferate in an unrestrained manner, metastasize and hijack normal biological function. Further, we capitalize on the power of our proteomic data to identify novel therapeutic drug-targets, and to develop microfluidic architectures for targeted detection of biomarkers indicative of disease.

  • Associate Professor, Department of Surgery, VT Carilion School of Medicine (2013-pres.) 
  • Associate Professor of Health Sciences, VT (2013-pres.) 
  • Associate Professor (affiliate), Chemistry, VT, Blacksburg, VA (2012-pres.) 
  • Associate Professor (affiliate), Genetics, Bioinformatics & Computational Biology, VT (2007-pres.) 
  • Associate Professor (affiliate), Biomedical Engineering, VT, VA (2005-pres.) 
  • Associate Professor, VBI/Biological Sciences, VT, Blacksburg, VA (2009-2010) 
  • Assistant Professor, VBI/Biological Sciences, VT, Blacksburg, VA (2003-2009) 
  • Principal Scientist, Barnett Institute/Northeastern University, Boston, MA (2000-2003) 
  • Postdoctoral Research, Oak Ridge National Laboratory, Oak Ridge, TN (1998-2000)
  • Postdoctoral Research, Sensar-Larson-Davis, Provo, UT (1997-1998)
  • Ph.D., Chemistry, Brigham Young University, Department of Chemistry and Biochemistry, Provo, UT, USA. Advisor: Prof. Milton L. Lee. Title: “Design of a Capillary Electrophoresis Time-of-Flight Mass Spectrometry System” 
  • M.Sc., Chemical Engineering/Organic Chemistry (1979-1984), Polytechnic Institute Traian Vuia, Chemical Engineering, Timisoara, Romania. Advisor: Prof. Radu Bacaloglu. Title: “Synthesis of Benzothiol Photosensitizers”Research Scientist, CCMP Solventul, Timisoara, Romania (1988-1992) 
  • Chemical Engineer, CIC Arad, Romania (1984-1987) 
  • Standing member, NIH Federal Advisory Committee/ISD (2018-2022) 
  • Virginia Tech Scholar of the Week, Blacksburg, VA, USA (Dec. 8, 2014) 
  • NSF CAREER Award, Virginia Tech, Blacksburg, VA, USA (2005) 
  • John N. Hatsopoulos Scholar Award, Northeastern University, Boston, MA, USA (2000) 
  • H. Tracy Hall Award, BYU, Provo, UT, USA (1996) 
  • Loren C. & Maurine F. Bryner Fellowship, BYU, Provo, UT, USA (1994) 
  • Chemistry Graduate Student National Competition, Iasi, Romania, 3rd place (1980)