Stephen Melville

Associate Professor
  • Ph.D., Microbiology, University of California at Davis, 1987
  • Postdoctoral Fellow, University of California at Los Angeles, 1988 - 1992
  • Postdoctoral Fellow and Lecturer, Tufts University School of Medicine, 1993 - 1995
melville
217 Life Sciences I Building (MC 0910)
970 Washington Street NW
Blacksburg, VA 24061
USA
  • Lab: (540) 231-8937

 

The Melville Lab Website

 

Major Field of Interest

Bacterial Pathogenesis

Current Research

  1. The interactions of the host immune system with the anaerobic bacterial pathogen Clostridium perfringens.  Specifically, the molecular mechanisms that allow the bacteria to avoid being killed by phagocytic cells of the immune system, macrophages and neutrophils
  2. The molecular regulation of toxin synthesis by C. perfringens, especially the enterotoxin that is responsible from food poisoning outbreaks
  3. The mechanism of pili-dependent gliding motility in C. perfringens