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Faculty

Klaus D Elgert

Professor Emeritus of Immunology

  • Ph.D., Immunology, University of Missouri School of Medicine, 1973
  • Postdoctoral: NIH Research Assoicate/NIH Fellowship, University of Missouri School of Medicine, 1974

Dr. Elgert's Immunology Website

Major Field of Interest

Tumor Immunology

Current Research

Assessment of tumor-induced phenotypic, cellular, and molecular changes of macrophages and how these changes affect the macrophages responsiveness to and production of cytokines. This involves three research initiatives: 

  1. The contribution of tumor-induced dysregulation of CD40L expression to macrophage dysfunction
  2. Tumor-induced modulation of IL-18 and IL-1β production through a macrophage and/or T cell NF-κB-associated event; can paclitaxel restore IL-18 and IL-1β production, and associated NF-κB activity during tumor growth
  3. Dysfunctional macrophage-mediated apoptosis and altered signal transduction during tumor growth
    elgert

  • (540) 231-6119
  • (540) 231-0771 (Lab)
  • kdelgert@vt.edu
  • Department of Biological Sciences (0406)
    Derring Hall RM 2097, Virginia Tech
    1405 Perry Street
    Blacksburg, VA 24061
    United States